G1 is enrolling a Phase 2 study of its intravenous inhibitor trilaciclib for the treatment of triple-negative breast cancer (TNBC), and a.
Trilaciclib: Experimental Treatment for Small-Cell Lung Cancer (SCLC). Scientific rationale and therapeutic potential. Trilaciclib is a short-acting inhibitor.
G1 Therapeutics (formerly G-Zero Therapeutics) is developing trilaciclib, a small- molecule inhibitor of cyclin dependent kinases for the treatment.
Trilaciclib - basketball
Prior hematopoietic stem cell or bone marrow transplantation. Other uncontrolled serious chronic disease or conditions that in the investigator's opinion could affect compliance or follow-up in the protocol. Choosing to participate in a study is an important personal decision. Trilaciclib is administered intravenously prior to chemotherapy and has the potential to significantly improve treatment outcomes. The company is advancing a pipeline of potential best-in-class and first-in-class drug candidates in multiple oncology indications. In combination, trilaciclib and Tecentriq have the potential to provide a powerful triple punch against small-cell lung cancer: anti-tumor activity, conservation of hematopoietic stem cells, and preservation or enhancement of immune system function. Triple Negative Breast Neoplasms. Other Study Trilaciclib Numbers:. Switch to audio verification. Please upgrade your browser or activate Google Chrome Frame to improve your experience. How to Apply for an Account. Other Sites About Clinical Trilaciclib. About the Results Database.
CDK 4/6 inhibitor, palbociclib, for the treatment of metastatic breast cancer
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Like what you are reading? Triple Negative Breast Cancer. Inhibiting these proteins temporarily stops hematopoietic stem and progenitor cells from dividing, making them resistant to damage from chemotherapy drugs that target dividing cells. To gain full access to the content and functionality of the AdisInsight database try one of the following.. In combination, trilaciclib and Tecentriq have the potential to provide a powerful triple punch against small-cell lung cancer: anti-tumor activity, conservation of hematopoietic stem cells, and preservation or enhancement of immune system function. No Study Results Posted.